Plain radiography in patients treated with intrathecal drug delivery using an implantable pump device

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Plain radiography in patients treated with intrathecal drug delivery using an implantable pump device

OBJECTIVES Intrathecal drug administration using an implanted pump system is well established in intractable spasticity and pain. However, despite continuous advancements in manufacturing technology, adverse events related to the pump and catheter still occur. Most of them, such as migration, damage, disconnection and occlusion, are related to the spinal catheter. The aim of this overview is to...

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Intrathecal Drug Delivery Therapy with Implantable Pump System in Refractory Cancer and Non-Cancer Pain

Chronic pain is the major cause of discomfort for any patient. Unfortunately there is still a present low efficacy of analgesic drugs to relief neuropathic pain [1]. The intrathecal drug delivery systems (IDDS) have been used for more than 30 years to deliver analgesic drugs into the cerebrospinal fluid and close to their site of action. These systems are being used in patients with both malign...

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Implantable Intrathecal Pump

It is useful for chemical neuromodulation of central nervous system to significantly reduce perception of pain by delivery of the drug. In simple terms, it is a completely internalized system comprising of an intrathecal catheter which is introduced in the fluid containing space around the spinal cord and connected to a drug reservoir sited in a pocket made under the skin. This facilitates admi...

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Design of an Implantable Device for Ocular Drug Delivery

Ocular diseases, such as, glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa require drug management in order to prevent blindness and affecting million of adults in USA and worldwide. There is an increasing need to develop devices for drug delivery to address ocular diseases. This study focuses on the design, simulation, and development of an impla...

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An Implantable MEMS Drug Delivery Device for Rapid Delivery in Ambulatory Emergency Care Citation

We introduce the first implantable drug delivery system based on MEMS (MicroElectro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD 3 (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac r...

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ژورنال

عنوان ژورنال: Insights into Imaging

سال: 2017

ISSN: 1869-4101

DOI: 10.1007/s13244-017-0568-z